#39: Kirstie Alley Was the Only Cheers Star Who Never Stopped by Frasier
During Frasier’s 11-season run, nearly every major Cheers character made at least one guest appearance — except Kirstie Alley. She was the only main cast member who never showed up on the hit spinoff, and the reason likely came down to personal beliefs.

As a Scientologist, Alley avoided projects centered on psychiatry. She’d even said she’d “never do a show about a psychiatrist,” which made Frasier’s entire premise a nonstarter for her. While Rebecca Howe never crossed paths with Frasier Crane again, Alley’s impact on Cheers remained unforgettable.
